{"id":273,"date":"2023-04-20T10:14:35","date_gmt":"2023-04-20T10:14:35","guid":{"rendered":"https:\/\/chungjansensyndrome.eu\/?page_id=273"},"modified":"2026-08-09T09:21:54","modified_gmt":"2026-08-09T09:21:54","slug":"about-phip","status":"publish","type":"page","link":"https:\/\/chungjansensyndrome.eu\/en\/","title":{"rendered":"About PHIP"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; admin_label=&#8221;Title Section&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_stops=&#8221;rgba(13,75,126,0.95) 0%|rgba(13,75,126,0.95) 100%&#8221; background_color_gradient_overlays_image=&#8221;on&#8221; background_image=&#8221;https:\/\/chungjansensyndrome.eu\/wp-content\/uploads\/2023\/02\/dna-1811955_1920.jpg&#8221; custom_margin=&#8221;-200px||||false|false&#8221; custom_padding=&#8221;250px||||false|false&#8221; custom_padding_tablet=&#8221;250px||||false|false&#8221; custom_padding_phone=&#8221;190px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Cognitive development&#8221; _builder_version=&#8221;4.20.4&#8243; text_font=&#8221;||||||||&#8221; header_font=&#8221;Montserrat|700|||||||&#8221; header_text_align=&#8221;center&#8221; header_text_color=&#8221;#f7f7f7&#8243; header_font_size=&#8221;60px&#8221; header_line_height=&#8221;1.3em&#8221; custom_margin=&#8221;||||false|false&#8221; header_font_size_tablet=&#8221;60px&#8221; header_font_size_phone=&#8221;30px&#8221; header_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1>Chung-Jansen Syndrome<\/h1>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Phone&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221; custom_margin=&#8221;||-100px||false|false&#8221; custom_margin_tablet=&#8221;||-100px||false|false&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;||||false|false&#8221; custom_padding_tablet=&#8221;||||false|false&#8221; custom_padding_phone=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Belangrijk Bericht&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||120px||false|false&#8221; custom_margin_tablet=&#8221;||120px||false|false&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||||false|false&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;First International Chung-Jansen Conference &#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf06a;||fa||900&#8243; icon_color=&#8221;#E09900&#8243; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;70px&#8221; content_max_width=&#8221;100%&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;Montserrat||||&#8221; body_text_color=&#8221;#747d88&#8243; body_line_height=&#8221;1.8em&#8221; body_link_font=&#8221;|700|||||||&#8221; body_link_text_color=&#8221;#E09900&#8243; text_orientation=&#8221;justified&#8221; custom_padding=&#8221;15px|15px|15px|15px|false|false&#8221; body_font_size_tablet=&#8221;&#8221; body_font_size_phone=&#8221;16px&#8221; body_font_size_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|2px|2px|2px|2px&#8221; border_color_all=&#8221;#E09900&#8243; global_colors_info=&#8221;{}&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221;]From <strong>July 23 through July 25<\/strong>, 2026, the first international Chung-Jansen conference will take place in Boston. You can still register via <a href=\"https:\/\/www.zeffy.com\/en-US\/ticketing\/cjs-conference-and-family-meeting\" target=\"blank\">the registration page<\/a>.<br \/>\nFor more information about the conference, please visit <a href=\"https:\/\/www.chung-jansen.org\/our-family-conference-and-meeting\/\" target=\"blank\">the conference information page<\/a>.<\/p>\n<p><a href=\"https:\/\/drive.google.com\/file\/d\/1lw1wkgOxbIVFPK6sFaY2-bdUjkTK2jDZ\/view?usp=drive_link\" target=\"blank\">Read the flyer<\/a>.[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Belangrijk Bericht&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||120px||false|false&#8221; custom_margin_tablet=&#8221;||120px||false|false&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||||false|false&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;First International Chung-Jansen Conference &#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf06a;||fa||900&#8243; icon_color=&#8221;#E09900&#8243; image_icon_width=&#8221;70px&#8221; content_max_width=&#8221;100%&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;Montserrat||||&#8221; body_text_color=&#8221;#747d88&#8243; body_line_height=&#8221;1.8em&#8221; body_link_font=&#8221;|700|||||||&#8221; body_link_text_color=&#8221;#E09900&#8243; text_orientation=&#8221;justified&#8221; custom_padding=&#8221;15px||15px||false|false&#8221; body_font_size_tablet=&#8221;&#8221; body_font_size_phone=&#8221;16px&#8221; body_font_size_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|2px|2px|2px|2px&#8221; border_color_all=&#8221;#E09900&#8243; global_colors_info=&#8221;{}&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221;]<\/p>\n<p>From <strong>July 23 through July 25<\/strong>, 2026, the first international Chung-Jansen conference will take place in Boston. You can still register via <a href=\"https:\/\/www.zeffy.com\/en-US\/ticketing\/cjs-conference-and-family-meeting\" target=\"blank\">the registration page<\/a>.<br \/>For more information about the conference, please visit <a href=\"https:\/\/www.chung-jansen.org\/our-family-conference-and-meeting\/\" target=\"blank\">the conference information page<\/a>.<\/p>\n<p><a href=\"https:\/\/drive.google.com\/file\/d\/1lw1wkgOxbIVFPK6sFaY2-bdUjkTK2jDZ\/view?usp=drive_link\" target=\"blank\">Read the flyer<\/a>.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221; width_tablet=&#8221;&#8221; width_phone=&#8221;90%&#8221; width_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;-100px||||false|false&#8221; custom_margin_tablet=&#8221;-100px||||false|false&#8221; custom_margin_phone=&#8221;20px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px|0px|0px|0px|false|false&#8221; custom_css_main_element=&#8221;z-index:1000;&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_color_tablet=&#8221;&#8221; box_shadow_color_phone=&#8221;rgba(0,0,0,0)&#8221; box_shadow_color_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;40px|0px|40px|40px|false|false&#8221; custom_padding_tablet=&#8221;40px|0px|40px|40px|false|false&#8221; custom_padding_phone=&#8221;0px|0px|0px|0px|false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;What is it?&#8221; _builder_version=&#8221;4.20.4&#8243; text_font=&#8221;Montserrat|500||on|||||&#8221; text_text_color=&#8221;#353740&#8243; text_font_size=&#8221;16px&#8221; text_letter_spacing=&#8221;3px&#8221; custom_margin=&#8221;||20px||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; animation_direction=&#8221;bottom&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]What is it?[\/et_pb_text][et_pb_divider color=&#8221;#E02B20&#8243; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;60px&#8221; custom_margin=&#8221;||15px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_image src=&#8221;https:\/\/chungjansensyndrome.eu\/wp-content\/uploads\/2023\/04\/in-short-mobile.jpeg&#8221; title_text=&#8221;in-short-mobile&#8221; disabled_on=&#8221;off|on|on&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.21.0&#8243; text_font=&#8221;Montserrat||||&#8221; text_text_color=&#8221;#747d88&#8243; text_line_height=&#8221;1.8em&#8221; link_font=&#8221;|700|||||||&#8221; link_text_color=&#8221;#0d4b7e&#8221; header_font=&#8221;||||||||&#8221; header_3_font_size=&#8221;18px&#8221; text_orientation=&#8221;justified&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; animation_direction=&#8221;top&#8221; text_font_size_tablet=&#8221;&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Chung-Jansen syndrome is a rare disorder- also called PHIP-related disorder. The syndrome is caused by a heterozygous mutation along the PHIP gene (<strong>6q14.1<\/strong>). Individuals with this disorder typically have developmental delay, behavioral problems, and are at risk for obesity. At present, the syndrome has been diagnosed in about 900 people worldwide. This number, however, is growing rapidly.<\/p>\n<p>Young children often have feeding difficulties and delayed developmental milestones like rolling, crawling, standing straight and walking. Speech and fine motor skills are often delayed as well.<\/p>\n<p>Just as in any gene disorder, the features and severity of problems can differ greatly between individuals with Chung-Jansen syndrome.<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;\/en\/about-phip\/syndrome-in-short\/&#8221; button_text=&#8221;Learn More&#8221; admin_label=&#8221;Learn More Button&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; button_text_color_hover=&#8221;#ffffff&#8221; button_border_color_hover=&#8221;#ffffff&#8221; button_letter_spacing_hover=&#8221;2px&#8221; button_bg_color_hover=&#8221;rgba(0,0,0,0)&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; 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custom_padding=&#8221;150px||0px||false|false&#8221; custom_padding_tablet=&#8221;150px||0px||false|false&#8221; custom_padding_phone=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; width_tablet=&#8221;&#8221; width_phone=&#8221;90%&#8221; width_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Psychological Development and Behavioral Disorders&#8221; _builder_version=&#8221;4.20.4&#8243; text_font=&#8221;Montserrat|500||on|||||&#8221; text_text_color=&#8221;#353740&#8243; text_font_size=&#8221;16px&#8221; text_letter_spacing=&#8221;3px&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;Montserrat|700||on|||||&#8221; header_2_font_size=&#8221;42px&#8221; header_2_line_height=&#8221;1.3em&#8221; text_orientation=&#8221;center&#8221; module_alignment=&#8221;center&#8221; animation_direction=&#8221;bottom&#8221; header_3_text_align_tablet=&#8221;&#8221; header_3_text_align_phone=&#8221;left&#8221; header_3_text_align_last_edited=&#8221;on|phone&#8221; header_3_font_size_tablet=&#8221;&#8221; header_3_font_size_phone=&#8221;16px&#8221; header_3_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Psychological Development and Behavioral Disorders<\/h3>\n<p>[\/et_pb_text][et_pb_divider color=&#8221;#E02B20&#8243; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;60px&#8221; module_alignment=&#8221;center&#8221; module_alignment_tablet=&#8221;center&#8221; module_alignment_phone=&#8221;left&#8221; module_alignment_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; padding_top_1=&#8221;0px&#8221; padding_top_2=&#8221;0px&#8221; padding_top_bottom_link_1=&#8221;false&#8221; padding_top_bottom_link_2=&#8221;false&#8221; padding_left_right_link_1=&#8221;false&#8221; padding_left_right_link_2=&#8221;false&#8221; module_class=&#8221;frontpage-specialty&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#f7f7f7&#8243; width_tablet=&#8221;&#8221; width_phone=&#8221;&#8221; width_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;0px||150px||false|false&#8221; custom_padding_tablet=&#8221;0px||150px||false|false&#8221; custom_padding_phone=&#8221;||190px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;Behavioral problems&#8221; _builder_version=&#8221;4.20.4&#8243; text_font=&#8221;Montserrat||||&#8221; text_text_color=&#8221;#747d88&#8243; text_line_height=&#8221;1.8em&#8221; header_font=&#8221;||||||||&#8221; text_orientation=&#8221;justified&#8221; width_last_edited=&#8221;off|phone&#8221; max_width=&#8221;300px&#8221; max_width_tablet=&#8221;300px&#8221; max_width_phone=&#8221;100%&#8221; max_width_last_edited=&#8221;on|phone&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|||&#8221; animation_direction=&#8221;bottom&#8221; text_font_size_tablet=&#8221;&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Behavioral problems are a striking and profound characteristic of the Chung-Jansen syndrome that children and adults have to deal with. This concerns rebellious and sometimes even (verbally) aggressive behavior that may be related to a developmental or behavioral disorder and \/ or learning delay.<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;\/en\/about-phip\/psychological-development-and-behaviour\/&#8221; button_text=&#8221;Learn more&#8221; button_alignment=&#8221;center&#8221; admin_label=&#8221;Learn More Button&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;b9bfcac8-355e-49c0-a7f5-baada7e02be3&#8243; custom_margin=&#8221;15px||||false|false&#8221; button_text_color_hover=&#8221;#ffffff&#8221; button_border_color_hover=&#8221;#ffffff&#8221; button_letter_spacing_hover=&#8221;2px&#8221; button_bg_color_hover=&#8221;rgba(0,0,0,0)&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_text_color__hover_enabled=&#8221;off|desktop&#8221; 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custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; animation_direction=&#8221;top&#8221; text_font_size_tablet=&#8221;&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Children with the syndrome are more hindered in learning gross and fine motor skills than other children of the same age.<br \/>\nChildren sometimes seem lazy and stubborn, but frustration about not being able to perform a certain task often lies behind this behavior.<br \/>\nThere often is a gap between verbal and performal skills. Individuals with the syndrome are verbally well developed. 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custom_padding_tablet=&#8221;40px|40px|40px|40px|false|false&#8221; custom_padding_phone=&#8221;0px|0px|0px|0px|false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Appearance&#8221; _builder_version=&#8221;4.19.5&#8243; text_font=&#8221;Montserrat|500||on|||||&#8221; text_text_color=&#8221;#353740&#8243; text_font_size=&#8221;16px&#8221; text_letter_spacing=&#8221;3px&#8221; custom_margin=&#8221;||||false|false&#8221; animation_direction=&#8221;bottom&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Appearance[\/et_pb_text][et_pb_divider color=&#8221;#E02B20&#8243; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;60px&#8221; custom_margin=&#8221;15px||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_image src=&#8221;https:\/\/chungjansensyndrome.eu\/wp-content\/uploads\/2023\/04\/features-mobile.jpeg&#8221; title_text=&#8221;features-mobile&#8221; disabled_on=&#8221;off|on|on&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.20.4&#8243; text_font=&#8221;Montserrat||||&#8221; text_text_color=&#8221;#747d88&#8243; text_line_height=&#8221;1.8em&#8221; header_font=&#8221;||||||||&#8221; text_orientation=&#8221;justified&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; animation_direction=&#8221;top&#8221; text_font_size_tablet=&#8221;&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>People with Chung-Jansen syndrome often have recognizable facial features, also called dysmorphic features.<\/p>\n<p><\/br><\/p>\n<ul>\n<li>Eyebrows (almost) fused together (synophris);<\/li>\n<li>Full eyebrows;<\/li>\n<li>Crease at the eyes (epicanthal folds);<\/li>\n<li>Upturned nose;<\/li>\n<li>Large ears and fleshy ear lobes;<\/li>\n<li>Fusion of the skin between the second and third toe (cutaneous syndactyly);<\/li>\n<li>A curved little finger (clinodactyly);<\/li>\n<li>Tapered fingers;<\/li>\n<li>Light brown spots on the skin (cafe au lait spot).<\/li>\n<\/ul>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; 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_builder_version=&#8221;4.20.4&#8243; text_font=&#8221;Montserrat|500||on|||||&#8221; text_text_color=&#8221;#353740&#8243; text_font_size=&#8221;16px&#8221; text_letter_spacing=&#8221;3px&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;Montserrat|700||on|||||&#8221; header_2_font_size=&#8221;42px&#8221; header_2_line_height=&#8221;1.3em&#8221; text_orientation=&#8221;center&#8221; module_alignment=&#8221;center&#8221; animation_direction=&#8221;bottom&#8221; header_3_text_align_tablet=&#8221;&#8221; header_3_text_align_phone=&#8221;left&#8221; header_3_text_align_last_edited=&#8221;on|phone&#8221; header_3_font_size_tablet=&#8221;&#8221; header_3_font_size_phone=&#8221;16px&#8221; header_3_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Physical Problems<\/h3>\n<p>[\/et_pb_text][et_pb_divider color=&#8221;#E02B20&#8243; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; 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divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;60px&#8221; custom_margin=&#8221;15px||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.21.0&#8243; text_font=&#8221;Montserrat||||&#8221; text_text_color=&#8221;#747d88&#8243; text_line_height=&#8221;1.8em&#8221; header_font=&#8221;||||||||&#8221; text_orientation=&#8221;justified&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; animation_direction=&#8221;top&#8221; text_font_size_tablet=&#8221;&#8221; text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]The syndrome is caused by a defect in the the PHIP gene encoding the pleckstrin homology domain-interacting protein. The PHIP gene (6q14.1) is located on chromosome 6. Individuals normally have two chromosomes 6 with two copies of the PHIP gene. 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You can still register via the registration page. For more information about the conference, please visit the conference information page. Read the flyer.From July 23 through July 25, 2026, the first international Chung-Jansen conference will take place [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-273","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/chungjansensyndrome.eu\/en\/wp-json\/wp\/v2\/pages\/273","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chungjansensyndrome.eu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/chungjansensyndrome.eu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/chungjansensyndrome.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/chungjansensyndrome.eu\/en\/wp-json\/wp\/v2\/comments?post=273"}],"version-history":[{"count":189,"href":"https:\/\/chungjansensyndrome.eu\/en\/wp-json\/wp\/v2\/pages\/273\/revisions"}],"predecessor-version":[{"id":210441,"href":"https:\/\/chungjansensyndrome.eu\/en\/wp-json\/wp\/v2\/pages\/273\/revisions\/210441"}],"wp:attachment":[{"href":"https:\/\/chungjansensyndrome.eu\/en\/wp-json\/wp\/v2\/media?parent=273"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}